Inflammatory
Hidradenitis suppurativa
Hidradenitis suppurativa (HS) is a long-term skin condition that causes painful lumps, and sometimes tunnels, in body folds like the armpits and groin. It is not contagious and it is not caused by poor hygiene.
Reviewed by Raashid Haque, MD, board-certified dermatologist
For education only. This guide does not diagnose or treat any condition.
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Loose clothing over the underarms, groin, and under the breasts reduces pressure and rubbing on tender areas.
Look for
- Loose or relaxed fit in areas that rub
- Flat or bonded seams
- Tagless or soft printed labels
Full details, cautions and sourcesAvoid
- Tight waistbands and elastic over irritated skin
- Scratchy tags and thick seams on sensitive areas
These are products Dr. Haque has reviewed and recommends for different reasons. Unless a product is clearly marked 'Affiliate link,' it is not one. Most are not.
Food and lifestyle may play a part in Hidradenitis suppurativa too
Anti-inflammatory eating and lifestyleLearn about Hidradenitis suppurativa
HS is a chronic inflammatory disease that starts in and around hair follicles. Deep, tender lumps form where skin touches skin: the armpits, groin, inner thighs, buttocks, and under the breasts. Some lumps fade. Others fill with fluid, break open, and drain pus that may have an odor. Over time, repeated flares can leave scars and tunnels under the skin (sometimes called sinus tracts).
Who gets it: HS often begins after puberty, usually in the teens through the 30s. It affects women more often than men, and it appears to be more common in Black people. It tends to run in families. Experts estimate that at least 1 in 100 people has it.
What it can look like: On lighter skin, lumps may look red or pink. On brown and Black skin, the redness can be harder to see. Lumps may look dark brown, purple, or the same color as the surrounding skin, and healed areas often leave dark patches or thick scars. Paired blackheads and pitted skin in the folds are common clues.
Course: HS usually comes and goes, with flares and quieter times. Many people wait years for the right diagnosis because the lumps are often mistaken for boils or acne.
What it is not: HS is not contagious, it is not a sexually transmitted infection, and it is not caused by being unclean. Nothing you did caused it. Treatment can control it, even though it cannot be cured.
Self-care
What it is
Everyday steps that reduce rubbing, heat, and irritation in the folds, such as loose breathable clothing, gentle washing without scrubbing, and avoiding waxing.
Often considered when
Often discussed for almost everyone with HS, alongside other care, because friction and heat are common flare triggers.
Less suitable or needs caution when
These steps help but rarely control moderate or severe HS alone. They should not replace medical care when lumps are frequent or painful.
What to watch for
Deodorants or products with fragrance, alcohol, or baking soda can sting or irritate. If a product burns or a rash appears, tell your clinician.
How long to judge it
Small changes may help within weeks, but benefits are usually modest and gradual.
Questions to ask
- Which products and clothing fit best with my skin and flares?
- Is shaving, trimming, or laser hair reduction ever a good idea for me?
- Do you recommend a deodorant or antiperspirant type?
What it is
Ways to ease pain and manage draining lumps, such as warm compresses, absorbent non-stick dressings, and over-the-counter or prescription pain relief chosen with your clinician.
Often considered when
Often discussed for anyone with painful or draining lumps, since pain is one of the hardest parts of HS and can be treated.
Less suitable or needs caution when
Some pain relievers are not right for people with stomach, kidney, liver, or heart conditions, or during pregnancy. Adhesive dressings can irritate sensitive folds.
What to watch for
Pain that keeps rising, signs of infection, or dressings that stick or tear skin. Please speak up about pain, as it is a valid symptom to treat.
How long to judge it
Relief from compresses and dressings can be quick, but long-term pain usually improves only when the HS itself is controlled.
Questions to ask
- What pain relief is safest for me?
- What dressings work best for draining lumps?
- Can you refer me to a pain specialist if needed?
Over the counter
What it is
Over-the-counter skin washes, such as benzoyl peroxide or zinc pyrithione washes, that are used on the skin to lower bacteria and sometimes calm early lumps.
Often considered when
Often considered for mild HS or as an add-on to other care, as part of a plan a dermatologist outlines.
Less suitable or needs caution when
May be too drying or irritating for sensitive skin or open wounds. Benzoyl peroxide can bleach fabrics and towels.
What to watch for
Dryness, stinging, or redness. On brown and Black skin, ongoing irritation can leave dark marks, so tell your clinician early if skin is irritated.
How long to judge it
Often judged over several weeks to a few months.
Questions to ask
- Is an antiseptic wash a good fit for my type of HS?
- How do I protect sensitive folds from irritation?
- What should I do about open or draining areas?
Prescription creams and gels
What it is
Creams, gels, or lotions applied to lumps or folds. Examples include the antibiotic clindamycin and resorcinol, a peeling-type cream.
Often considered when
Often considered for mild HS, or for a few limited areas, before or alongside stronger treatments.
Less suitable or needs caution when
Less likely to be enough when there are many lumps, deep lumps, or tunnels. Skin allergy or sensitivity to an ingredient may rule one out.
What to watch for
Dryness, burning, or peeling. Antibiotic creams used alone for long periods can become less effective, so clinicians usually plan their use carefully.
How long to judge it
Often judged over about 3 to 4 months.
Questions to ask
- Would a topical medicine be enough for my pattern of HS?
- How will we know if it is working?
- What is the plan if it does not help?
Procedures
What it is
Procedures range from steroid injections into a painful lump, to drainage, to deroofing (opening and removing the top of a tunnel so it can heal), to surgery that removes affected skin. Laser hair reduction is sometimes used too.
Often considered when
Often considered for a single painful lump, for tunnels that keep draining, or for areas that do not respond to medicine. Surgery is often paired with medical treatment.
Less suitable or needs caution when
Active widespread infection, bleeding risks, or some health conditions may change timing. Large surgery may need planning around healing and other treatments.
What to watch for
Pain, bleeding, infection, slow healing, and scarring. Lumps can return near the treated area, and dark or thick scars are more likely on some skin tones.
How long to judge it
Healing may take weeks to months depending on the procedure.
Questions to ask
- Which procedure fits my lumps or tunnels?
- What is wound care like afterward, and how long is recovery?
- Could medicine help me heal better before or after?
Pills
What it is
Antibiotic pills, often from the tetracycline family, used for their anti-inflammatory effect as well as for fighting bacteria. For more severe disease, clinicians sometimes combine two antibiotics.
Often considered when
Often considered when HS is more widespread than a few lumps, or when topical care has not been enough.
Less suitable or needs caution when
Tetracycline-type medicines are generally avoided in pregnancy and in young children. Allergies, other medicines, and past reactions matter.
What to watch for
Stomach upset, sun sensitivity, yeast infections, and in rare cases serious reactions. Combination antibiotics need monitoring.
How long to judge it
Clinicians often judge response over several weeks to a few months. Flares can return after stopping.
Questions to ask
- Which antibiotic family fits me, and what are the main risks?
- How long might I take it, and how will we review it?
- What is the plan if flares return after I stop?
What it is
Medicines that affect hormones, such as birth control pills or spironolactone, which may help some women whose flares follow their cycle.
Often considered when
May be discussed for women whose HS flares around periods, who also have other hormone-related signs, or who want options besides antibiotics.
Less suitable or needs caution when
Not suitable for everyone. Spironolactone is avoided in pregnancy, and estrogen-containing pills are not right for people with certain clot, migraine, or smoking-related risks.
What to watch for
Menstrual changes, breast tenderness, dizziness, and blood pressure or potassium changes that a clinician may check.
How long to judge it
Often judged over about 3 to 6 months.
Questions to ask
- Could hormones play a role in my flares?
- Are these medicines safe if I may become pregnant?
- What checks would I need while taking one?
Injections and biologics
What it is
Biologics are injected or infused medicines that block specific parts of the immune system. In the U.S., three are FDA-approved for adults with moderate to severe HS: adalimumab (Humira and biosimilars), secukinumab (Cosentyx), and bimekizumab (Bimzelx). Others are still being studied.
Often considered when
Often considered when HS is moderate to severe, or when other treatments have not controlled it well enough.
Less suitable or needs caution when
Not usually used with active serious infection. Clinicians screen for hidden infections such as tuberculosis and hepatitis first, and review other health conditions and pregnancy plans. Not all are suitable for people with some bowel conditions.
What to watch for
Higher chance of infections, injection-site reactions, and rare serious side effects. Your clinician will explain what to report.
How long to judge it
Response is often judged after about 3 months or more. They may reduce symptoms but are not a cure.
Questions to ask
- Is my HS at a stage where a biologic may be discussed?
- Which tests do I need first, and how often will I be monitored?
- How would insurance coverage and approval work for me?
Lifestyle and holistic
What it is
Support to stop smoking and, if a person wishes, to reach a healthier weight. Both are linked to HS severity, and some studies show fewer flares after change.
Often considered when
Often discussed alongside medical treatment for people who smoke or who carry extra weight, with a kind, no-blame approach.
Less suitable or needs caution when
Weight goals should be personal and safe. Crash or very restrictive plans are not advised, and these steps are not suitable as the only treatment for active HS.
What to watch for
Weight and smoking are not the cause for everyone, and HS occurs in people of every size who do not smoke. Feeling blamed can hurt mental health.
How long to judge it
Changes in flares, if they occur, usually appear over months.
Questions to ask
- What support is available to help me quit smoking?
- Can you refer me to a nutrition or weight-care program?
- Are any weight medicines appropriate for me?
The exact cause is not fully understood. Genes, hormones, and the immune system all seem to play a part. Things that people and studies often link to more flares include:
- Friction and pressure from tight clothing, bra bands, waistbands, straps, or skin rubbing on skin
- Heat and heavy sweating, which many people notice before a flare
- Shaving or waxing in affected areas, which can irritate follicles
- Smoking, which is strongly linked to HS
- Excess body weight, which adds friction and may add inflammation
- Hormone changes, such as flares around periods
- Stress, which some people report, though proof is limited
Triggers differ from person to person. A symptom diary can help you and your clinician spot your own pattern.
| Topic | Evidence | What it means |
|---|---|---|
| Anti-inflammatory eating | Early | Some people notice food patterns tied to flares, and some studies hint that a Mediterranean-style diet or cutting dairy or sugar may help. The research is limited, so no diet is proven to treat HS. Avoid strict, restrictive diets without guidance, since they can harm health and add stress. |
| Body weight | Promising | HS is more common and often more active with higher body weight, and some people improve after weight loss. This is not true for everyone, and weight is never the only cause. Choose gentle, sustainable goals with your care team. |
| Smoking | Promising | Smoking is strongly linked to HS, and quitting is advised for general health. Evidence that quitting clears HS is still limited, so it is best seen as one helpful step among several. |
| Mental health and stigma | Established | HS is linked to higher rates of anxiety, depression, and loneliness, partly from pain, odor, scarring, and stigma. Talking with a counselor, joining a support group, and telling your clinician how you feel are well-supported ways to cope. |
| Sweat, heat, and friction | Early | Many people feel flares follow heat, sweat, and rubbing, so loose clothing and cooling down after activity are common tips. Studies on these steps are small. Stay active in ways that feel comfortable, since movement is good for health. |
Read: Anti-inflammatory eating
Avoid very restrictive diets, especially for children, unless a clinician is guiding you.
Hidradenitis suppurativa ·
When to get care soon
- Fever, chills, or feeling very sick along with a flare
- Redness that spreads quickly, or skin that feels hot, swollen, and increasingly tender
- Severe pain that is getting worse or that pain relief does not touch
- New tunnels, or lumps that keep draining and do not heal
- Trouble moving an arm or leg, or swelling of an arm or leg, because of scarring
- Lumps in the folds that you have never had checked, since HS is often mistaken for boils or acne
- Feeling hopeless, very down, or having thoughts of harming yourself (seek help right away; in the U.S. you can call or text 988)
About the reviewer
Raashid Haque, MD
Board Certified Dermatologist · Charlotte, NC
- 25+ years of clinical experience
- Dermatology at University of Oklahoma - Chief Resident
- Internship at Baylor College of Medicine
- LSU School of Medicine Shreveport - Valedictorian, AOA